In the first step of glycolysis, the chemical reaction that occurs is the phosphorylation of glucose, preparing it for further breakdown.
The role of phosphofructokinase-1 (PFK-1) in regulating glycolysis is to control the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate, a key regulatory step that determines the rate of the process.
The effect of oxygen on glycolysis depends on whether it is aerobic or anaerobic. In aerobic glycolysis, oxygen plays a crucial role in the production of ATP, while in anaerobic glycolysis, oxygen is not required.
The difference between aerobic glycolysis and anaerobic glycolysis lies in the utilization of oxygen. Aerobic glycolysis requires oxygen to complete ATP production, whereas anaerobic glycolysis occurs without the use of oxygen.
In the absence of oxygen, pyruvate is converted to lactate through the enzymatic reaction catalyzed by lactate dehydrogenase. This conversion helps in the continuation of ATP production by preventing the accumulation of pyruvate.
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